EUFLEXXA®

What Is Euflexxa Injection?

Euflexxa is a sterile, non-pyrogenic hyaluronic acid-based orthopaedic injection specifically formulated to treat knee osteoarthritis.

This is a clear, sterile solution composed of a highly purified form of hyaluronic acid (sodium hyaluronate). This hyaluronic acid is a large molecule (2.4-3.6 million daltons) extracted from bacterial cells.

Its structure consists of repeating sugar units (N-acetylglucosamine and sodium glucuronate) linked together in a specific pattern (alternating beta 1,3 and beta 1,4 glycosidic bonds).

It is the first bioengineered hyaluronic acid approved in the United States with a natural-like molecular structure, closely resembling human synovial fluid. Euflexxa works by restoring the viscoelastic properties of synovial fluid, providing lubrication and shock absorption in the knee joint, thus reducing pain and improving mobility.

This product is ideal for patients who have not responded well to conservative treatments such as oral pain relievers or physical therapy.

Visit the Nu Derma Supply online store and buy Euflexxa Injections to provide patients with a non-surgical, effective treatment option that has been clinically proven to reduce pain and improve the quality of life in osteoarthritis sufferers.

What Is Euflexxa Injection Used for?

Euflexxa injections are used for multiple therapeutic purposes in managing knee osteoarthritis:

• Reducing chronic knee pain in patients with osteoarthritis.
• Improving joint mobility and flexibility by enhancing lubrication.
• Delaying the need for knee replacement surgery in patients with advanced osteoarthritis.
• Providing pain relief when other treatments such as NSAIDs and corticosteroids have failed.
• Supporting recovery post-arthroscopy by reducing inflammation and promoting joint healing.

Using Euflexxa Injection for Knee

Yes. Euflexxa is specifically designed for the knee joint and is administered as a series of three weekly injections.

It is ideal for patients with mild to moderate osteoarthritis who seek pain relief without resorting to surgery. The treatment is well-tolerated and can significantly improve knee function and reduce pain for up to six months.

What Is Comparable to Euflexxa?

Two notable alternatives to Euflexxa are Monovisc and Orthovisc, which contain hyaluronic acid.

Monovisc offers a single-injection treatment, which may be more convenient for some patients, while Orthovisc is administered in a series of three to four injections.

These Euflexxa injection alternatives, just like Euflexxa, provide symptomatic relief for knee osteoarthritis by improving joint lubrication and reducing pain.

Who Is the Manufacturer of Euflexxa Shots?

Euflexxa is produced by Ferring Pharmaceuticals Inc., a global biopharmaceutical company headquartered in Switzerland.

Ferring specialises in innovative treatments in orthopaedics, reproductive health, gastroenterology, and urology. The company is committed to researching and developing biologics and other innovative therapies that address unmet medical needs.

Benefits and Results of Using Euflexxa Injections

Euflexxa injections offer numerous benefits for managing knee osteoarthritis:

• Pain relief: Provides effective reduction of knee pain associated with osteoarthritis.
• Improved mobility: Enhances joint function, allowing for easier movement.
• Long-lasting effects: Relief can last months post-treatment.
• Delays surgery: Helps patients postpone the need for knee replacement surgery.
• Minimally invasive: Non-surgical option for patients not responding to other treatments.
• High safety profile: Low risk of adverse reactions compared to other treatments.
• Quick recovery: Minimal downtime is required after the procedure.
• Increased quality of life: Patients often report significant improvements in daily activities.

Euflexxa Shots Main Ingredients and Device Properties

Euflexxa is composed of the following ingredients and has specific properties that make it effective for joint pain relief:

Main ingredients

• Sodium hyaluronate: 10 mg.
• Sodium dihydrogen phosphate dihydrate: 0.05 mg.
• Disodium hydrogen phosphate dodecahydrate: 0.56 mg.
• Sodium chloride: 8.5 mg.
• Water for injection: q.s.

 

Device properties

• Pre-filled syringes: Each syringe is pre-loaded with 2 ml of solution, ensuring accurate dosing and easy administration.
• Sterile and non-pyrogenic: The solution is free from bacteria and toxins, minimising the risk of infections and complications.
• Bioengineered formulation: Euflexxa’s unique structure closely mimics natural synovial fluid, making it highly compatible with the human body.

Accessories or Items Included

Euflexxa is supplied with the following:

• 3 disposable pre-filled syringes: Each syringe contains 2 ml of Euflexxa solution.
• Sterile packaging: Ensures product safety and integrity.
• Instructions for use: Comprehensive guidelines for proper administration and handling.

Storage Conditions

Proper storage of Euflexxa is essential for maintaining its effectiveness:

• Store between 2°C and 25°C.
• Keep it in the original packaging to protect it from light and contamination.
• Do not freeze the product, as freezing can alter its effectiveness.
• Refrigerated products should be allowed to reach ambient temperature for approximately 20-30 minutes prior to use.

Mode of Administration

Euflexxa should be administered by a qualified healthcare professional following these steps:

Pre-procedure:

• Review the patient’s medical history for allergies and contraindications.
• Ensure the injection site is clean and free of infection or skin lesions.
• Obtain informed consent after explaining the procedure and potential risks.

 

During procedure:

• Use a sterile technique to withdraw the product from the syringe.
• Insert the needle into the knee joint space using an aseptic technique.
• Administer the entire content of the syringe slowly, ensuring proper placement of the solution within the synovial cavity.

 

After procedure:

• Remove the needle carefully and apply a sterile bandage to the injection site.
• Advise the patient to avoid strenuous activities for 48 hours.
• Monitor for any immediate adverse reactions, such as swelling or discomfort.

Post-Treatment Care

Patients should follow these guidelines after receiving the Euflexxa injections:

• Avoid high-impact activities like running, tennis, hiking, or heavy lifting for 48 hours.
• Apply ice to the injection site for 10-15 minutes every hour if swelling or discomfort occurs.
• Take acetaminophen for pain relief, but avoid NSAIDs immediately after the injection to prevent interference with the treatment.
• Rest and elevate the leg as needed to reduce swelling and promote recovery.
• Resume normal activities gradually, as tolerated, to avoid placing stress on the treated knee.
• Report any unusual symptoms such as severe pain, persistent swelling, or signs of infection to the healthcare provider immediately.

How Long Do Euflexxa Effects Last?

Euflexxa injections typically provide relief for up to 6 months.

Patients may require repeat treatments twice a year to maintain the benefits, depending on the severity of their osteoarthritis and their individual response to therapy.

Euflexxa Injection Side Effects

While Euflexxa is generally well-tolerated, some side effects may occur:

Common side effects:

• Mild pain or swelling at the injection site.
• Temporary redness or warmth in the treated knee.
• Mild bruising around the injection area.
• Headache or dizziness following the injection.
• Joint swelling.
• Pain in extremities and the back.
• Musculoskeletal pain.
• Arthritis.
• Arthralgia.
• Localised skin reactions such as itching or rash.

 

Rare side effects:

• Severe allergic reactions: Symptoms may include hives, swelling, and difficulty breathing.
• Infection at the injection site: Signs include increased pain, redness, and fever.
• Severe knee pain or swelling: This may indicate improper injection or joint irritation.
• Bleeding or haematoma formation: Especially in patients with bleeding disorders.

Contraindications for the Euflexxa 20mg/ml Treatment

Euflexxa should not be used in the following situations:

• Patients with known allergies to hyaluronic acid or similar substances.
• Active infections in the knee joint or skin around the injection site.
• Patients with severe liver or kidney disease due to potential metabolic interactions.
• Severe bleeding disorders or those on anticoagulant therapy due to an increased risk of bleeding.
• Pregnant or breastfeeding women: Safety has not been established.
• Acute joint inflammation or injury: Should be treated before administering Euflexxa.

What Do Euflexxa Injection Reviews Say?

Medical professionals and patients have provided positive feedback on Euflexxa, highlighting its effectiveness in reducing knee pain and improving joint function.

Patients appreciate the non-surgical option and the extended period of relief, while clinicians value the product’s ease of use and consistent results.

Can Euflexxa Be Self Administered?

No. Euflexxa injections should only be administered by qualified healthcare professionals.

Self-administration can lead to improper injection, complications, and increased risk of adverse effects.

Who Can Buy Euflexxa Injections and Where?

Only certified medical professionals, such as orthopaedic surgeons, rheumatologists, and general practitioners with experience in joint injections, can purchase Euflexxa online.

Buying from verified and authorised vendors like Nu Derma Supply ensures the product’s authenticity and safety.

Do You Need a Prescription for Hyaluronic Acid Injection?

Yes, hyaluronic acid injections like Euflexxa require a prescription.

They should only be used under the supervision of a healthcare professional to ensure proper administration and monitoring.

How Much Does Euflexxa Injection Cost?

The cost of Euflexxa injections varies based on the treatment area, the number of injections required, and the healthcare provider’s fees.

Generally, the price ranges between £250 and £500 per treatment course.

How Much Does a Hyaluronic Acid Injection Cost in the UK?

Hyaluronic acid injections in the UK can range from £200 to £600 per treatment, depending on the product used, the clinic, and the number of sessions required.

Does Medicare Cover Euflexxa Injections?

Medicare may cover Euflexxa injections under specific conditions.

Coverage is typically provided if conservative treatments have failed, and the patient is diagnosed with knee osteoarthritis. However, it is crucial to check with individual insurance plans for exact coverage details.