Nucleofill dermal filler is a cutting-edge biostimulant gel made from natural polynucleotides and characterised by high viscosity, designed for skin rejuvenation and protection. As an anti-aging treatment, Nucleofill enhances skin elasticity and firmness while helping to prevent wrinkles. Promoitalia’s flagship line, Nucleofill, comprises four specialised products, each tailored to address specific skin concerns.
Buy Nucleofill online today.
Renowned for its advanced cross-linked hyaluronic acid technology, Nucleofill is a premier choice for aesthetic treatments, including wrinkle reduction and lip augmentation. This line of dermal fillers offers effective, non-surgical solutions for individuals seeking facial rejuvenation.
Nucleofill is a specialised range of skin boosters designed to achieve various skincare goals by acting on three levels: lifting, antioxidant protection, and hydration. Unlike typical skin boosters, Nucleofill does not contain hyaluronic acid. Instead, it uses high molecular weight polynucleotide chains to protect and rejuvenate the skin. These polynucleotides stimulate type 1 collagen production and transform fibroblasts into myofibroblasts, enhancing skin structure and hydration.
The unique biochemical properties of these polynucleotides grant the product high viscoelasticity and a strong ability to bind water, providing intense moisture and deep hydration. Additionally, Nucleofill delivers a potent bio-stimulating effect, encouraging skin regeneration through a three-way mechanism.
Nucleofill is produced by Promoitalia, a renowned Italian company specialising in advanced aesthetic treatments.
Nucleofill products are composed of polymerized polynucleotides in a transparent gel form, derived from salmon cells.
In aesthetic medicine, polynucleotides extracted from salmon DNA are used due to their remarkable compatibility with human skin and their potent hydrating and tissue-regenerating abilities.
Nucleofill is manufactured using the unique PDRN complex from salmon cells, undergoing a multi-stage purification process. PDRNs are DNA fragments that penetrate cells and repair molecular damage. These polynucleotides are safe, natural, and highly effective.
Polynucleotides activate receptors on skin fibroblasts, transforming them into myofibroblasts. This boosts the production of type I collagen and elastin, tightening and lifting the skin. The product eliminates free radicals and provides antioxidant protection, as well as bind water, ensuring long-term hydration of the extracellular matrix. This process helps the skin regenerate, thicken, and strengthen, resulting in improved skin tone, reduced wrinkles, and enhanced moisture and elasticity.
Nucleofill is a range of high-viscosity biostimulating gels, formulated with natural polynucleotides to protect and rejuvenate the skin. These injectables offer four distinct types of skin stimulation:
Nucleofill is indicated for all skin types, regardless of their maturity and it can help with more than just signs of aging, as it helps addresses various skin concerns, including dehydrated skin, signs of exposure to oxidative stress (pollution, sun, tobacco, lifestyle), scars, stretch marks and more.
The Nucleofill range offers specialised products designed for various skin concerns and rejuvenation goals:
Nucleofill provides a comprehensive solution for achieving smoother, more defined, and naturally rejuvenated skin. Here are some of the key advantages:
Typically, the results last from three to six months. After that, maintenance treatments may be recommended to sustain the desired results over time.
As with any dermal filler treatment, there are potential side effects and risks to consider. Common and temporary adverse effects may include:
More serious complications are rare but can occur, so it’s essential to follow post-treatment care instructions and seek prompt medical attention if any concerning symptoms arise.
Nucleofill products are entirely natural and safe, and they do not contain substances with sensitising potential. Still, specific contraindications may make it unsuitable for some patients that have:
Nucleofill products are available for purchase by licensed medical professionals, including dermatologists, cosmetic surgeons, and aesthetic practitioners. These professionals use Nucleofill to provide advanced skin rejuvenation treatments to their patients.
When purchasing Nucleofill products online, it is crucial to choose official suppliers to ensure the product’s authenticity and safety. Official suppliers, like Nu Derma Supply, guarantee that you receive genuine Nucleofill products that meet the highest standards of quality and efficacy.
Join our newsletter to receive latest news and offers
Medicle MD Ltd
Reg. Number: 14317237
Address: 27 Old Gloucester Street,
WC1N 3AX London,
United Kingdom