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Refine+ Soft



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Refine+ Filler Soft 20mg/ml is a smooth, non-animal, stabilized, cross-linked hyaluronic acid-based filler and skin booster. Skin boosters work by injecting small amounts of hyaluronic acid into the skin, which stimulates the production of collagen and elastin fibers. This results in improved skin elasticity and a reduction in fine lines and wrinkles. This product is designed to provide long-lasting hydration, stimulate the production of new collagen in the skin, and even out skin tone. The Refine+ Filler Soft is ideal for use in rejuvenating all skin types, and can be used to treat the face, neck, and hands.


Reshape the neckline, face and hands

Refine+ Filler Soft is a versatile filler that can be used to improve the appearance of various areas on the body. It is particularly effective at addressing sagging skin in the neck and jawline, but can also be used to improve volume loss and wrinkles on the face and hands.

Injected to hydrate and create a protective layer to keep your skin’s natural glow

Refine+ Filler Soft has a unique ability to hydrate the skin from within, creating a natural and healthy-looking glow. By increasing hydration levels, the filler also helps to protect the skin from environmental stressors that can lead to premature aging. A higher concentration of hyaluronic acid (20mg/ml) may provide even more hydration to the skin, resulting in a more significant improvement in skin quality and texture.

Improves texture and tone of the skin and helps prevent the signs of aging

Refine+ Filler Soft is designed to stimulate the production of collagen in the skin, which helps to improve skin texture and tone over time. As we age, collagen production slows down, leading to the appearance of wrinkles, fine lines, and other signs of aging. Refine+ Filler Soft can help to reverse these effects and prevent further damage.

For mature or photodamaged skin, reduces appearance of fine lines or imperfections

Refine+ Filler Soft is an ideal choice for patients with mature or photodamaged skin, as it can effectively reduce the appearance of fine lines, wrinkles, and other imperfections. By improving skin texture and tone, Refine+ Filler Soft can help patients achieve a more youthful and refreshed appearance. With a higher concentration, it is possible that patients may see more significant improvement in their skin quality and texture. Additionally, it can be used to fill in deeper lines and wrinkles, providing a more dramatic improvement in the overall appearance of the skin.

Recommended protocols

In Spring, the Refine+ Filler Soft should be used to prevent dehydration while sun exposure. We recommend three treatments every 2-3 weeks.

In Summer, the Refine+ Filler Soft is used to maintain the desired hydration level in the skin while protecting the fibroblasts from the cytotoxic action of free radicals. The cellular alimentation and activity should also be increased. We recommend one treatment every 4-6 weeks during the summer period, followed by a maintenance treatment every 6 months for long-lasting results.

In Autumn, the Refine+ Filler Soft is used to prepare the skin for changing weather conditions, from dry and cold air to aircon and heating exposure. The Refine+ Filler Soft provides long-term hydration through HA reservoirs. We recommend four treatments every 2-3 weeks, followed by a maintenance treatment every 4 months for long-lasting results.


It’s important to note that using a higher concentration of hyaluronic acid in skin boosters may also increase the risk of adverse reactions, such as swelling or bruising. It’s important to ensure that patients are fully informed of the potential risks and benefits of the treatment, and that they are suitable candidates for the higher concentration product. To ensure a safe treatment with Refine Filler products, it is essential to assess patients’ medical history and suitability. The use of the Refine+ Filler Soft is contraindicated in the following cases:

  • Allergy to components present in the product
  • Pregnancy or breastfeeding
  • Injection in areas with skin problems (infection, inflammation)

Refine+ Filler Soft is composed of a smooth, stabilized, and cross-linked hyaluronic acid with a concentration of 20mg/mL, in a physiological solution of sodium chloride with a pH of 7. The pack contains one graduated pre-filled syringe for 1 ml and two 30G needles, making it easy and convenient to use.

It is important to note that this product must be administered only by a professional authorized to inject hyaluronic acid-based filling products.

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